I have dozens and dozens of articles in my e-folders discussing the health benefits of coffee.  But this isn’t about coffee.  It’s about Ivermectin.

Your colon, which is also known as the large intestine, plays an incredibly important role in your health. As part of the digestive tract, bacteria in the colon are responsible for the final breakdown of food material before it passes into the rectum and is excreted through the anus.

New evidence published in Frontiers in Pharmacology show the antiparasitic medication ivermectin may have a new application in the treatment of colorectal cancer (CRC). Researchers are hopeful this may have a positive impact on colon cancer deaths. Colon cancer is the third leading cancer diagnosis and third cause of cancer death in the U.S.

According to data from the National Cancer Institute, an estimated 149,500 new cases of colorectal cancer will be diagnosed in 2021 and an estimated 52,980 people will die. This represents 7.9% of all new cases of cancer diagnosed in 2021 and 8.7% of all cancer deaths.

There are modifiable risk factors associated with colorectal cancer. For example, lifestyle factors over which you have control that reduce your risk of colorectal cancer include your diet, alcohol consumption, activity level, weight and history of smoking.

Wrongly vilified as a “livestock drug” by the media in the treatment of COVID-19 with “scant evidence it works,” researchers have found a new use for this Nobel Prize-winning medication. As the research team wrote in the published study, although CRC is the third most common cancer worldwide, it still lacks effective therapy.

Past research has demonstrated that ivermectin also has anti-inflammatory, antitumor and antiviral properties. To test the influence ivermectin may have on colorectal cancer cells, the team used cancer cell lines SW480 and SW1116. Both are epithelial cell lines from the large intestine in humans.

The researchers used multiple tests to determine cell viability and apoptosis after exposure to ivermectin. They also measured reactive oxygen species levels and cell cycle. To explore the effect on proliferation, the researchers used different concentrations of ivermectin on the cultured cells and found cell viability decreased in a dose-dependent and time-dependent manner.

The ivermectin also altered cell morphology, demonstrating a decrease in cells after just 24 hours and a loss of their original shape. Cultured cells were also exposed to concentrations of ivermectin after which cell viability and apoptosis were measured. The researchers found an increase in apoptosis indicating a dose-dependent effect.

Additionally, the researchers measured the activity of Caspase-3 that plays a vital role initiating apoptosis. They found that ivermectin increases Caspase 3/7 activity in both cell lines in a dose-dependent manner.

Source (more at the link).

Uh oh.  The FDA and big Pharma won’t like this one tiny little bit.  They hate you and want to see you die.